SpCas9 Nuclease-mRNA

SpCas9 mRNA encodes the widely used CRISPR nuclease for efficient genome editing in mammalian cells. Delivery of mRNA enables rapid, transient Cas9 expression that reduces persistent nuclease exposure while supporting robust editing when paired with synthetic sgRNAs in research workflows.

• Enables efficient gene knockout and precise sequence modification
• Pairs with synthetic gRNAs for high on-target editing performance
• Supports transient nuclease expression for controlled editing activity
• Suitable for ex vivo cell engineering and in vivo genome editing research