Showing 1–12 of 72 results
SpCas9 mRNA encodes the widely used CRISPR nuclease for efficient genome editing in mammalian cells. Delivery of mRNA enables rapid, transient Cas9 expression that reduces persistent nuclease exposure while supporting…
hfCas12Max mRNA encodes a high-fidelity Cas12 nuclease engineered for precise genome editing with reduced off-target activity. Transient mRNA delivery enables controlled nuclease expression while supporting efficient editing when paired with…
This validated controls kit is engineered for SpCas9 gene editing in human cells. It enables the precise assessment of cleavage efficiency and specificity by providing benchmark positive and negative gRNAs…
eSpOT-ON nuclease is an engineered high-fidelity Cas9 protein designed for therapeutic applications. It offers high on-target editing efficiency while minimizing off-target activity, making it a safer choice for precise cell…
eSpOT-ON is an engineered high-fidelity Cas9 variant, designed for therapeutic gene editing. Delivered in mRNA format, eSpOT-ON provides superior on-target activity with low off-target effects. This nuclease has been validated…
hfCas12Max is a high-fidelity CRISPR nuclease engineered for therapeutic genome editing. It offers high on-target and low off-target editing across various cell types. Its small size and broad PAM sequence…
AccuBase™ is an engineered cytosine base editor designed for therapeutic applications. It enables precise single-base conversions from C to T, minimizing off-target activity and eliminating the risk of double-strand breaks.…
SpCas9 nuclease is a high-quality, recombinant protein that enables robust and reliable genome editing. This widely used CRISPR nuclease, complexed with a synthetic single guide RNA (sgRNA), can achieve high…
Proofreading hot‑start polymerase delivers higher fidelity than Taq with robust amplification of mid‑length targets. Produces blunted products for cloning and is well-suited for NGS library amplification.Higher fidelity than Taq; proofreadingRobust…
T4 RNA Ligase II joins 3'-OH RNA to 5'-phosphorylated oligos within duplex contexts, reducing adapter dimers and artifacts. It produces cleaner small RNA libraries and supports dsRNA nick sealing and…
In IVT, accumulating pyrophosphate (PPi) inhibits T7 and other RNA polymerases. Inorganic pyrophosphatase hydrolyzes PPi to phosphate, preventing product inhibition and sustaining transcription for higher, cleaner mRNA yields at standard…
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