CRISPR Resources | Synthego

CRISPR to the Clinic and Beyond

Learn more about clinical applications of CRISPR and how Synthego can support you from early-phase research, through process development, and into the clinic, highlighting our new sgRNA GMP manufacturing capabilities

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Shaping Therapeutic Development with Cutting-Edge CRISPR Nucleases

This live webinar recording explores Synthego’s cutting-edge nuclease portfolio, featuring our newest engineered nuclease, eSpOT-ON. Casey Jowdy, Senior Product Manager at Synthego, dives into its development, how its on-target and off-target profile (fidelity) compares to other Cas9 variants, and demonstrates its therapeutic potential by treating familial hypercholesterolemia. Through detailed data analysis, you will gain a deeper understanding of how eSpOT-ON enhances genome editing efficiency and how you can start using it in your work today.

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hfCas12Max: A Novel Nuclease for CRISPR-based Cell and Gene Therapies

Over the last decade, CRISPR gene editing has revolutionized both practical research and the development of cell and gene therapies. The choice of the nuclease and gRNA format is often...

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Selecting the Right Gene and Transcript for CRISPR editing

Designing guides for your CRISPR experiments is crucial. Watch this webinar to learn how to use precise gene nomenclature and select the primary transcript for designing high-quality guides for CRISPR...

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Advancing Direct Enzyme Delivery For Therapeutic Genome Editing In Vivo

CRISPR-based genome editing is emerging as a frontrunner in gene therapy research. Conventionally, viral vectors, and more recently, nanoparticles have been the choice of delivery platforms in vivo. Watch this...

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CRISPR Technologies for the New Era of Cell and Gene Therapy

Cell and gene therapies are revolutionizing next-generation therapeutics. Many researchers are now leveraging the power of CRISPR precision genome engineering in their cell and gene therapies research, from fixing mutations...

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Webinar: Using CRISPR to Develop Transgenic Mice

CRISPR-Cas9 genome editing has transformed gene function studies, thus enabling validation of new drugs and treatments quickly and precisely. Since its introduction in 2012, CRISPR technology has also been a...

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Protein Analysis of Knockouts Webinar

Protein analysis of CRISPR mediated gene editing is an important method for validating a functional gene knockout. Choosing an appropriate protein analysis assay and using the right controls, is the...

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Forge a Successful CRISPR Therapeutic Path with High-Quality GMP sgRNA

CRISPR cell and gene therapies are predicted to be the future of medicine, yet developing these therapies presents researchers with a variety of challenges. Ensuring the quality, efficacy, and consistency...

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Discovery to Clinic: CRISPR-based Therapies and Diagnostics

With CRISPR being a key component of this revolution in treatments and even cures, the industry is seeing a massive increase in demand for clinical-grade guide RNA. Synthego has established...

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Clinical-Grade gRNA for Genomic Medicines: Making Sense of the CRISPR Regulatory Landscape

The regulatory landscape governing CRISPR-based therapeutic development is evolving and uncertain. In this webinar, you will learn how Synthego's industry-leading Regulatory Affairs team leverages intelligence in the Cell & Gene...

Videos

Enabling GMP Production of sgRNA for CRISPR-based Cell and Gene Therapies

For over a decade, facilitating Research Use Only (RUO) CRISPR studies has resulted in an increasing number of CRISPR-based cell and gene therapies used to treat patients with debilitating diseases....