For over a decade, we have been helping scientists make groundbreaking discoveries that transform the scientific community and lead to innovative therapeutic breakthroughs.
See more about what they are doing with our CRISPR solutions to uncover how we can be your Guide towards gene editing success.
Thanks to Synthego, I can now embark on any gene knock-out and HDR experiment in human pluripotent stem cells with extreme confidence it will work. These reagents are nothing short of an absolute game-changer for our group.
Using the RNP format is the only way [to achieve high editing efficiencies]. I've tried doing it with plasmids or DNA in general, and the B cells just rejected it. But the RNP was really, really effective.
The guide RNA Cas9 complex worked well for us. We had ordered 3 different guides, and all of them gave a great Knockdown for a highly expressed protein on a suspension NK cell line.
We always get significantly higher editing efficiencies with Synthego's sgRNAs compared to in vitro transcribed sgRNAs.
Synthego's synthetic sgRNA will accelerate our ability to use CRISPR as a gene editing teaching tool by reducing the amount of lab time required while increasing the overall quality of experiments.
It was easy and works great. It's also time-saving!
Synthego sgRNAs cut down months of screening for knockouts and made my life much easier.
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