CRISPR has opened the door to new opportunities in functional genomics screening. By perturbing thousands of genes, researchers can investigate the genetic underpinnings of diseases at scale. In this comprehensive eBook, we review CRISPR screens with a focus on target identification within the drug discovery pipeline.

CRISPR loss-of-function screens are compelling tools that can be used to interrogate gene function at scale. We’ve created an introductory guide that describes the basics.

Our eBook includes the following:

  • Introduction to Genetic Screens
  • Genetic Screens in Drug Discovery
  • Functional Assays
  • Pooled vs. Arrayed Workflows
  • Delivery Formats & Library Design

If you are new to CRISPR screens but are ready to dive in, this is a great place to start. Learning a new technique can be daunting, but this resource can start you off on the right foot.