CRISPR-Cas9 genome editing has transformed gene function studies, thus enabling validation of new drugs and treatments quickly and precisely. Since its introduction in 2012, CRISPR technology has also been a game-changer for creating knockout mice and other mutant animal models.

But is it easy to master CRISPR? What are the technological caveats to consider? And finally, once new models are generated, how do we best ensure the most efficient propagation of these genetically engineered rodents?

Hear from Dr. Chris Dowdy from Charles River Laboratories, Inc and Dr. Kevin Holden, Head of Science at Synthego and learn more about:

  • Critical steps in the CRISPR workflow
  • Best practice for generating CRISPR-edited mice
  • The challenges of breeding and maintaining complex mutant rodent lines